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A study of Salmonella typhi isolated in Suez Canal area. Biotyping, phage typing and colicinogenic property
Abstract:
In this work a total of 82 strains of Salmonella typhi were isolated from Egyptian patients diagnosed as quiry enteric fever. These cases were from Ismalia, Suez and port Said Areas. The strains fell in 16 phage types. Phage types N, 40, E1, and degraded Vi were the commonest phage type in Ismailia, while phage types degraded Vi and C1 were the commonest in Port Said. Phage types Di-N, degraded Vi, A and C1 were the commonest in Suez. Chemotyping of Salmonella typhi showed that the majority of the strains belonged to chemotype I (82%), and the rest belonged to chemotype II (18%). Colicin production was negative and all the strains were susceptible to the currently used antibiotics.
Insights
This study analyzed 82 Salmonella typhi strains from Egyptian enteric fever patients, identifying 16 phage types and confirming susceptibility to common antibiotics. Most strains belonged to chemotype I.
Area of Science:
- Microbiology
- Infectious Diseases
- Epidemiology
Background:
- Enteric fever, caused by Salmonella typhi, remains a significant public health concern in Egypt.
- Understanding the epidemiological characteristics of Salmonella typhi strains is crucial for effective disease control.
Purpose of the Study:
- To characterize Salmonella typhi strains isolated from enteric fever patients in Egypt.
- To determine the phage types, chemotypes, and antibiotic susceptibility patterns of these strains.
Main Methods:
- Isolation and identification of 82 Salmonella typhi strains from patients in Ismailia, Suez, and Port Said.
- Phage typing and chemotyping of the isolated strains.
- Assessment of colicin production and antibiotic susceptibility testing.
Main Results:
- A total of 82 Salmonella typhi strains were isolated and classified into 16 distinct phage types.
- Chemotype I was predominant (82%), followed by chemotype II (18%).
- All strains exhibited negative colicin production and were susceptible to currently used antibiotics.
Conclusions:
- The study provides valuable insights into the phage typing and chemotyping of Salmonella typhi in Egypt.
- The observed antibiotic susceptibility suggests that current treatment regimens may remain effective against these strains.