Lethal Necrotizing Cellulitis Caused by ESBL-Producing E. Coli after Laparoscopic Intestinal Vaginoplasty

Area of Science:

• Surgical reconstruction
• Transgender health
• Infectious disease

Background:

• Absence of a functional vagina negatively impacts quality of life.
• Vaginal reconstruction aims to improve well-being.
• Various surgical techniques exist for vaginal reconstruction.

Observation:

• An 18-year-old transgender woman underwent laparoscopic intestinal vaginoplasty.
• Post-operative complications included septic shock and multiple organ failure.
• Infection was caused by extended-spectrum β-lactamase-producing Escherichia coli.

Findings:

• Necrotizing fasciitis developed and progressed rapidly.
• Despite intensive treatment, the complication was lethal.
• This highlights a rare but severe risk associated with the procedure.

Implications:

• Vaginal reconstruction positively influences quality of life for transgender women.
• Healthcare providers and patients must be aware of potential serious complications.
• Vigilance for resistant bacterial infections is crucial after such procedures.