Relationship Between Accelerometer-Measured Activity and Self-Reported or Performance-Based Function in Older Adults...

Area of Science:

• Cardiology
• Geriatrics
• Biomedical Engineering

Background:

• Aortic stenosis (AS) significantly impacts physical activity and functional status in older adults.
• Current assessment methods, including patient-reported outcomes and performance tests, may not fully capture daily physical activity.
• Objective measurement of physical activity using accelerometry could provide complementary clinical information.

Purpose of the Study:

• To determine if accelerometer-measured physical activity provides distinct clinical information in older adults with severe AS.
• To compare accelerometer data with self-reported surveys and performance-based function tests.
• To evaluate the utility of accelerometry as an objective measure of physical activity in this population prior to transcatheter aortic valve replacement (TAVR).

Main Methods:

• Wrist-mounted accelerometry was used to measure daily daytime activity (M10) in 52 older adults with severe AS.
• Participants completed various baseline surveys (e.g., NYHA, SF-12, KCCQ, EQ-5D) and performance-based function tests (e.g., SPPB, 6-min walk, grip strength).
• Linear regression models assessed the relationships between accelerometer data and survey/performance test results.

Main Results:

• Weak, non-meaningful correlations were found between M10 and SF-12 Mental Composite Score, and between M10 and grip strength in univariable analyses.
• Multiple linear regression models showed no significant correlation between M10 and overall survey data or performance-based function tests.
• Accelerometer-measured physical activity (M10) did not correlate significantly with commonly used self-reported surveys or performance-based function tests.

Conclusions:

• Accelerometer-measured physical activity provides distinct clinical information in older adults with severe AS, independent of self-reported surveys and performance-based function tests.
• Objective accelerometry offers a valuable, complementary tool for assessing physical activity in AS patients.
• These findings support the integration of accelerometry into clinical practice for a more comprehensive evaluation of functional status in AS patients undergoing TAVR.