The JRC Nanomaterials Repository: A unique facility providing representative test materials for nanoEHS research

Area of Science:

• Nanomaterial safety testing
• Regulatory science
• Environmental health and safety research

Background:

• The European Commission established a Nanomaterials Repository for globally distributed, industrially manufactured nanomaterials.
• These nanomaterials have undergone testing in the OECD Testing Programme and EU-funded research projects.
• The repository now serves the global scientific community in nanoEHS (nanomaterial environmental health and safety) research.

Purpose of the Study:

• To describe the design of a state-of-the-art facility for semi-automated subsampling of nanomaterials.
• To ensure customized, precise, and safe preparation of nanomaterial vials for worldwide distribution.
• To support regulatory research and the development of OECD regulatory test guidelines.

Main Methods:

• Design and implementation of a semi-automated subsampling procedure within the JRC Nanomaterials Repository.
• Utilizing a state-of-the-art installation for customized sub-sampling under safe conditions.
• Ensuring traceability of final sample vials distributed for research purposes.

Main Results:

• The Repository facility enables flexible and precise preparation of nanomaterial vials.
• The semi-automated procedure guarantees operator safety and environmental protection.
• The JRC nanomaterials are representative of the global market, facilitating comparable research data.

Conclusions:

• The JRC Nanomaterials Repository is a vital resource for global nanoEHS research.
• The described subsampling procedure enhances the reliability and comparability of nanomaterial safety testing.
• The repository's function supports the advancement of international regulatory frameworks for nanomaterials.