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Updated: Mar 14, 2026

On-line Analysis of Nitrogen Containing Compounds in Complex Hydrocarbon Matrixes
Published on: August 5, 2016
Determination of isocyanate groups in the organic intermediates by reaction-based headspace gas chromatography
1State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou, China; School of Materials Science and Engineering, South China University of Technology, Guangzhou, China.
Abstract:
This work reports on a novel method for the determination of isocyanate groups in the related organic intermediates by a reaction-based headspace gas chromatography. The method is based on measuring the CO2 formed from the reaction between the isocyanate groups in the organic intermediates and water in a closed headspace sample vial at 45°C for 20min. The results showed that the method has a good precision and accuracy, in which the relative standard deviation in the repeatability measurement was 5.26%, and the relative differences between the data obtained by the HS-GC method and the reference back-titration method were within 9.42%. The present method is simple and efficient and is particularly suitable to be used for determining the isocyanate groups in the batch sample analysis.
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