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Updated: Mar 14, 2026

Amplification of Escherichia coli in a Continuous-Flow-PCR Microfluidic Chip and Its Detection with a Capillary Electrophoresis System
Published on: November 21, 2023
Recent advances in enhancing the sensitivity of electrophoresis and electrochromatography in capillaries and
Michael C Breadmore1,2,3, Alain Wuethrich1, Feng Li1
1Australian Centre of Research on Separation Science, School of Physical Science, University of Tasmania, Hobart, Tasmania, Australia.
Abstract:
One of the most cited limitations of capillary (and microchip) electrophoresis is the poor sensitivity. This review continues to update this series of biennial reviews, first published in Electrophoresis in 2007, on developments in the field of on-line/in-line concentration methods in capillaries and microchips, covering the period July 2014-June 2016. It includes developments in the field of stacking, covering all methods from field amplified sample stacking and large volume sample stacking, through to isotachophoresis, dynamic pH junction, and sweeping. Attention is also given to on-line or in-line extraction methods that have been used for electrophoresis.
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