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Defining the Path Forward: Guidance for Laboratory Medicine Guidelines.

Stephen E Kahn1, Patricia M Jones2, Alex C Chin3

  • 1Department of Pathology, Loyola University Health System, A Member of Trinity Health , Maywood, IL, USA.

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Summary
This summary is machine-generated.

The National Academy of Clinical Biochemistry (NACB) and American Association of Clinical Chemistry (AACC) have refined their guideline development process. This evolution, influenced by Institute of Medicine (IOM) reports, ensures high-quality laboratory medicine practice guidelines (LMPGs).

Keywords:
AGREE IIevidence-based laboratory medicineevidence-based medicinelaboratory management practice guidelinestandard operating procedure

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Area of Science:

  • Clinical Laboratory Science
  • Evidence-Based Medicine
  • Healthcare Policy

Background:

  • The National Academy of Clinical Biochemistry (NACB) has a 20-year history of developing consensus-based guidelines for laboratory evaluation and monitoring.
  • Standardization efforts began in 1997 with the first Standard Operating Procedure (SOP) for guideline development.
  • The Evidence-Based Laboratory Medicine Committee (EBLMC), formed in 2010 by the American Association of Clinical Chemistry (AACC) and NACB, oversees guideline development.

Purpose of the Study:

  • To describe the NACB and EBLMC experience in developing Laboratory Medicine Practice Guidelines (LMPGs).
  • To highlight the evolution and application of the latest SOP for guideline development.
  • To discuss current practices, tools, and challenges in developing LMPGs collaboratively.

Main Methods:

  • Revision of the Laboratory Medicine Practice Guidelines (LMPG) SOP, influenced by 2011 Institute of Medicine (IOM) reports.
  • Continued development of LMPGs at a rate of approximately one per year.
  • Collaborative development with multiple clinical societies and professional organizations.

Main Results:

  • NACB has a consistent track record of developing LMPGs, with roughly one guideline published annually.
  • The latest SOP revision incorporates best practices and addresses recommendations from IOM reports.
  • Three LMPGs are currently in various stages of development, all involving collaboration with external groups.

Conclusions:

  • The NACB and AACC have established a robust framework for developing evidence-based laboratory medicine guidelines.
  • Collaboration with other professional organizations is a key strategy for current and future guideline development.
  • Ongoing refinement of processes, guided by external standards, ensures the continued production of high-quality LMPGs.