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Pedunculated carcinoma ex pleomorphic adenoma of the nasal cavity: A unique case report
Po-Wu Liao1, Yen-Lin Chen, Jeng-Wen Chen
1aDepartment of Otorhinolaryngology-Head and Neck Surgery, Catholic Yonghe Cardinal Tien Hospital bDepartment of Pathology, Cardinal Tien Hospital cSchool of Medicine, Fu-Jen Catholic University dDepartment of Otorhinolaryngology-Head and Neck Surgery, Cardinal Tien Hospital, New Taipei City, Taiwan.
Background:
A carcinoma ex pleomorphic adenoma (CXPA) is an epithelial malignancy arising in or from a benign pleomorphic salivary adenoma. The parotid gland is the most common location of CXPAs. Minor salivary gland CXPAs of the nasal cavity are exceedingly rare, with only 6 documented in the literature.
Methods And Result:
We present a 7th case: an unusual pedunculated intranasal CXPA, which had a favorable outcome after a wide endoscopic excision and the longest follow-up period reported to date. The clinical features, immunohistochemical characteristics, treatment choices, and disease outcomes of the intranasal CXPAs reported in previous studies are also reviewed.
Conclusion:
This case demonstrates the importance of considering the possibility of CXPA in the differential diagnosis of minor salivary gland malignancies in the nasal cavity.
