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Related Experiment Videos

Illegal use patterns, side effects, and analytical methods of ketamine.

Eunyoung Han1, Nam Ji Kwon1, Ling-Yi Feng2

  • 1College of Pharmacy, Duksung Women's University, Seoul, Republic of Korea; Duksung Innovation Center, Republic of Korea.

Forensic Science International
|September 30, 2016
PubMed
Summary

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Ketamine (KT) is a prevalent illicit drug in Asia, with significant mental and physical side effects. This review examines KT

Area of Science:

  • Forensic Toxicology
  • Pharmacology
  • Drug Abuse Research

Background:

  • Ketamine (KT) is a widely abused illicit drug, particularly in Asian countries like China, Taiwan, and Hong Kong.
  • KT abuse is associated with numerous adverse mental and physical health effects.
  • Global regulations exist for ketamine, highlighting its controlled status in nations such as Korea, the U.S.A., and Australia.

Purpose of the Study:

  • To review the pharmacology and adverse effects of ketamine.
  • To explore patterns of illicit ketamine use.
  • To analyze and compare analytical methods for ketamine detection in biological samples (urine and hair) and quantify its concentrations in abusers versus non-abusers.

Main Methods:

  • Comprehensive literature review focusing on ketamine's pharmacology, side effects, and illicit use.
Keywords:
Illegal ketamine useKetamineSide effects of ketamineUrinalysis and hair analysis of ketamine

Related Experiment Videos

  • Detailed analysis of various analytical methods for ketamine detection in biological matrices.
  • Comparison of key parameters across different analytical techniques, including sample preparation, instrumentation, and detection limits.

    • Main Results:

    • Identified significant mental and physical health problems associated with ketamine abuse.
    • Compared parameters of urine and hair analysis methods for ketamine, including extraction techniques, internal standards, and cutoff values.
    • Reported differences in ketamine concentrations between drug abusers and non-abusers.

    Conclusions:

    • There is a critical need for developing rapid and precise analytical methods for detecting illicit ketamine use in real-world samples.
    • Effective harm reduction strategies require careful assessment, early identification, and surveillance of ketamine users.
    • Stricter legislative control and preventive education, especially for young populations, are essential to combat the rising trend of illegal ketamine use.