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Updated: May 31, 2026

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Development of a Lateral Flow Immunochromatographic Strip for Rapid and Quantitative Detection of Small Molecule Compounds
Published on: November 13, 2021
On-site strip-type drug test kit enhanced by AI-based image analysis
Sora An1, Joong Lee2, Sangki Lee1
1Department of Forensic Science, Sungkyunkwan University, Suwon 16419, the Republic of Korea.
Summary
A new artificial intelligence (AI) image analysis method significantly improves the accuracy of strip-type drug test kits. This AI approach enhances reliability in field drug detection, outperforming human analysis.
Area of Science:
- Forensic Science
- Analytical Chemistry
- Artificial Intelligence
Background:
- Increasing demand for rapid, precise field drug detection due to beverage tampering incidents.
- Existing strip-type drug tests rely on subjective visual interpretation, leading to variability.
- Need for objective, quantitative methods to improve drug test kit reliability.
Purpose of the Study:
- To develop and validate a user-friendly, portable strip-type drug test kit.
- To implement an AI-based image analysis method for objective result interpretation.
- To enhance the automation and reliability of field drug detection.
Main Methods:
- Development of a novel strip-type drug test kit minimizing hazardous reagents and waste.
- Utilized artificial intelligence (AI) image analysis techniques for quantitative evaluation.
- Trained and evaluated deep-learning models (CNN, ViT, CNN-GRU) on 7,295 kit images.
Main Results:
- The CNN-GRU model demonstrated superior performance in accuracy, precision, recall, F1-score, and Cohen's kappa (1.0000).
- AI algorithm achieved perfect accuracy, exceeding the performance of 32 police officers.
- Validated AI-based precision reading algorithms for strip-type drug test kits.
Conclusions:
- AI-based precision reading algorithms significantly enhance automation and reliability of strip-type drug test kits.
- The developed method offers a reliable solution for field drug detection in forensic and investigative settings.
- This technology has strong potential for improving accuracy and reducing errors in drug testing.

