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Updated: Mar 14, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Melanomas
Caterina Longo1, Giovanni Pellacani2
1Skin Cancer Unit, Arcispedale S. Maria Nuova-IRCCS, Viale Risorgimento, 80, Reggio Emilia 42100, Italy.
Abstract:
Melanomas are a wide range of tumors that differ in their epidemiology, morphology, genetic profile, and biological behavior. They can be grouped as superficial spreading melanoma, lentigo maligna, and nodular melanoma. Reflectance confocal microscopy is useful for the evaluation of skin lesions that are dermoscopically doubtful by increasing diagnostic accuracy and specificity. This article provides a comprehensive overview of the different confocal main morphologies of distinct melanoma types as a function of the anatomic location of the tumor.
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