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Related Concept Videos

Atomic Absorption Spectroscopy: Atomization Methods01:25

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Atomic Absorption Spectroscopy (AAS) atomizes samples through flame atomization or electrothermal atomization. Flame atomization typically involves a nebulizer and spray chamber assembly to combine the sample with a fuel–oxidant mixture, creating a fine aerosol mist that enters a burner. Typically, the fuel and oxidant are combined in an approximately stoichiometric ratio. However, for atoms that are easily oxidized, a fuel-rich mixture may be more advantageous. Only about 5% of the...
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Aqueous Droplets Used as Enzymatic Microreactors and Their Electromagnetic Actuation
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Pharmaceutical and biomaterial engineering via electrohydrodynamic atomization technologies.

Prina Mehta1, Rita Haj-Ahmad1, Manoochehr Rasekh1

  • 1Leicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.

Drug Discovery Today
|October 4, 2016
PubMed
Summary
This summary is machine-generated.

Electrohydrodynamic atomization (EHDA) engineers complex micro- and nano-structures for healthcare. This review highlights EHDA advances in pharmaceutical and biomaterial applications, crucial for drug delivery and tissue regeneration.

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Pharmaceutical Sciences

Background:

  • Micro- and nano-structures are vital for advancements in healthcare, including pharmaceuticals and biomaterials.
  • Key healthcare challenges like advanced chemotherapy, diagnostics, and tissue regeneration require innovative solutions.
  • Electrohydrodynamic atomization (EHDA) is an emerging technology with significant potential in these areas.

Purpose of the Study:

  • To review recent and established advances in electrohydrodynamic atomization (EHDA).
  • To focus on the pharmaceutical and biomaterial applications of EHDA-engineered micro- and nano-structures.

Main Methods:

  • EHDA technology relies on electric fields acting on conductive fluids to form a Taylor cone.
  • Engineering of micro- and nano-structures involves optimizing process parameters, material properties, nozzle design, and collection methods.

Main Results:

  • EHDA enables the creation of complex active micro- and nano-structures.
  • These structures have promising applications in advanced chemotherapy, biomedical diagnostics, and tissue regeneration.

Conclusions:

  • EHDA is a versatile technology for fabricating micro- and nano-structures for healthcare.
  • Continued optimization of EHDA processes will drive further innovation in pharmaceutical and biomaterial sciences.