Related Experiment Video
Updated: Mar 14, 2026

Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis
Published on: October 4, 2024
Factors Associated with Increased Pain in Primary Dysmenorrhea: Analysis Using a Multivariate Ordered Logistic
María I Tomás-Rodríguez1, Antonio Palazón-Bru2, Damian R J Martínez-St John3
1Department of Pathology and Surgery, Miguel Hernández University, San Juan de Alicante, Alicante, Spain.
Study Objective:
In the literature about primary dysmenorrhea (PD), either a pain gradient has been studied just in women with PD or pain was assessed as a binary variable (presence or absence). Accordingly, we decided to carry out a study in young women to determine possible factors associated with intense pain.
Design:
A cross-sectional observational study.
Setting:
A Spanish University in 2016.
Participants:
A total of 306 women, aged 18-30 years.
Interventions:
A questionnaire was filled in by the participants to assess associated factors with dysmenorrhoea.
Main Outcome Measures:
Our outcome measure was the Andersch and Milsom scale (grade from 0 to 3).
Definition:
grade 0 (menstruation is not painful and daily activity is unaffected), grade 1 (menstruation is painful but seldom inhibits normal activity, analgesics are seldom required, and mild pain), grade 2 (daily activity affected, analgesics required and give relief so that absence from work or school is unusual, and moderate pain), and grade 3 (activity clearly inhibited, poor effect of analgesics, vegetative symptoms and severe pain).
Results:
Factors significantly associated with more extreme pain: a higher menstrual flow (odds ratio [OR], 2.11; P < .001), a worse quality of life (OR, 0.97; P < .001) and use of medication for PD (OR, 8.22; P < .001).
Conclusion:
We determined factors associated with extreme pain in PD in a novel way. Further studies are required to corroborate our results.
More Related Videos
07:36Analysis of Raw and Processed Cyperi Rhizoma Samples Using Liquid Chromatography-Tandem Mass Spectrometry in Rats with Primary Dysmenorrhea
Published on: December 23, 2022
06:22Ex Vivo Method for Assessing the Mouse Reproductive Tract Spontaneous Motility and a MATLAB-based Uterus Motion Tracking Algorithm for Data Analysis
Published on: September 1, 2019
Related Concept Videos
Disorders of the Female Reproductive System
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Analgesia and Pain Management
Factors Affecting Illness
For instance, risk factors are connected to illness,...
Factors affecting Blood pressure
Physiological Factors:
Factorial Design