Tribulus terrestris Extract Improves Human Sperm Parameters In Vitro

Area of Science:

• Reproductive Biology
• Pharmacology

Background:

• Male infertility affects a significant portion of the population.
• Herbal extracts are increasingly explored for their potential therapeutic effects on reproductive health.

Purpose of the Study:

• To evaluate the direct impact of Tribulus terrestris extract on key human sperm parameters.
• To determine the optimal concentration of Tribulus terrestris extract for enhancing sperm function.

Main Methods:

• Human semen samples from healthy donors were divided into control and experimental groups.
• Experimental groups were incubated with varying concentrations (20, 40, 50 µg/mL) of Tribulus terrestris extract.
• Sperm motility, viability, and DNA fragmentation were assessed over time.

Main Results:

• Tribulus terrestris extract at 40 and 50 µg/mL significantly increased total sperm motility, progressive motility, and curvilinear velocity.
• Sperm viability was also significantly enhanced by the extract.
• No significant effects on DNA fragmentation were mentioned in the provided text.

Conclusions:

• In vitro application of Tribulus terrestris extract positively influences human sperm parameters.
• These findings suggest a potential role for Tribulus terrestris in improving male fertility.