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Updated: Mar 14, 2026
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Analysis of Minerals Produced by hFOB 1.19 and Saos-2 Cells Using Transmission Electron Microscopy with Energy Dispersive X-ray Microanalysis
Published on: June 24, 2018
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Demineralization-remineralization dynamics in teeth and bone.
Ensanya Ali Abou Neel1, Anas Aljabo2, Adam Strange2
1Division of Biomaterials, Operative Dentistry Department, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi Arabia; Biomaterials Department, Faculty of Dentistry, Tanta University, Tanta, Egypt; Department of Biomaterials and Tissue Engineering, UCL Eastman Dental Institute, London, UK.
International Journal of Nanomedicine
|October 4, 2016
Summary
Biomineralization research explores how organisms form mineralized tissues like bone and teeth. Understanding this process aids in developing treatments for mineralization diseases and innovative biomaterials.
Area of Science:
- Biomineralization and biomaterials science.
- Focus on inorganic nanocrystal precipitation within organic matrices.
- Applications in dental and bone tissue engineering.
Background:
- Biomineralization is a lifelong process creating biological tissues like enamel, dentin, cementum, and bone.
- Understanding mineral deposition is crucial for treating mineralization-related diseases and developing scaffolds.
- Teeth and bone are susceptible to demineralization throughout life, with teeth exhibiting higher resistance.
Purpose of the Study:
- To provide an overview of biomineralization mechanisms and influencing factors.
- To describe the role of calcium and phosphate in teeth and bone health.
- To discuss demineralization-remineralization processes and novel therapeutic technologies.
Main Methods:
- Review of current theories on biomineralization mechanisms.
- Analysis of factors affecting mineralization (agonists and antagonists).
- Discussion of demineralization-remineralization processes in teeth and bone.
- Exploration of emerging technologies for tissue repair and regeneration.
Main Results:
- Detailed examination of mineralization theories and influencing factors.
- Elucidation of calcium and phosphate roles in skeletal and dental health.
- Comparison of demineralization-remineralization dynamics in teeth versus bone.
- Introduction of advanced composites mimicking natural tissue properties for enhanced repair.
Conclusions:
- Biomineralization knowledge is vital for advancing treatments for mineralization disorders.
- Novel technologies, including mineral composites, offer promising avenues for natural tissue repair.
- Translating these innovations into practice can significantly improve global healthcare outcomes.
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