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Updated: Mar 14, 2026

Studying Effects of Cigarette Smoke on Pseudomonas Infection in Lung Epithelial Cells
Published on: May 11, 2020
Pathophysiology, research challenges, and clinical management of smoke inhalation injury
Perenlei Enkhbaatar1, Basil A Pruitt2, Oscar Suman3
1Department of Anesthesiology, University of Texas Medical Branch, Galveston, TX, USA.
Abstract:
Smoke inhalation injury is a serious medical problem that increases morbidity and mortality after severe burns. However, relatively little attention has been paid to this devastating condition, and the bulk of research is limited to preclinical basic science studies. Moreover, no worldwide consensus criteria exist for its diagnosis, severity grading, and prognosis. Therapeutic approaches are highly variable depending on the country and burn centre or hospital. In this Series paper, we discuss understanding of the pathophysiology of smoke inhalation injury, the best evidence-based treatments, and challenges and future directions in diagnostics and management.
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