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Related Experiment Video

Updated: Mar 14, 2026

Author Spotlight: Effect of Left Atrial Ligation on Avian Embryonic Hearts and HLHS Implications

Author Spotlight: Effect of Left Atrial Ligation on Avian Embryonic Hearts and HLHS Implications

Published on: June 16, 2023

Hypoplastic left heart syndrome: current perspectives.

Christopher E Greenleaf¹, J Miguel Urencio¹, Jorge D Salazar¹

¹University of Mississippi Medical Center, 2500 North State Street, Jackson MS 39216, USA.

Translational Pediatrics

|October 7, 2016

Summary

This summary is machine-generated.

Hypoplastic left heart syndrome (HLHS) treatment has advanced significantly, transforming a fatal diagnosis into a manageable condition. This review explores current HLHS management options, including surgical palliation, transplant, and hybrid approaches.

Keywords:

Hypoplastic left heart syndrome (HLHS)congenital cardiac anomalies single ventricle

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Area of Science:

Cardiology
Pediatric Surgery
Congenital Heart Disease

Background:

Hypoplastic left heart syndrome (HLHS) was historically a fatal diagnosis.
Significant advancements in pre-, intra-, and postoperative care have improved outcomes.
The Norwood procedure in 1983 marked a turning point in HLHS intervention.

Approach:

This paper reviews current trends and perspectives in HLHS treatment.
It details five distinct management strategies.
The focus is on contemporary approaches to pediatric heart conditions.

Key Points:

Norwood stage I as the start of 3-stage palliation.
Heart transplantation as a viable option.
True hybrid and hybrid-bridge-to-Norwood procedures.
Compassionate care for unreconstructible cases.

Conclusions:

HLHS management has evolved dramatically, offering multiple therapeutic pathways.
Current options provide tailored solutions from palliative care to complex surgical interventions.
The outlook for HLHS patients has improved substantially due to medical progress.