Quantitative Systems Pharmacology: A Case for Disease Models.

C J Musante1, S Ramanujan2, B J Schmidt3

  • 1Pfizer Inc, Cambridge, Massachusetts, USA.

Summary

Quantitative systems pharmacology (QSP) offers innovative model-informed drug discovery and development. Disease-scale platform QSP models provide unique, reusable value for diverse clinical decisions, distinct from other strategies.

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Pharmacodynamic Models: Link Model and Systems Pharmacodynamic Model01:14

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Pharmacodynamic Models: Direct Effect Model and Indirect Response Model01:29

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