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Updated: Mar 14, 2026
Polymer Microarrays for High Throughput Discovery of Biomaterials
Published on: January 25, 2012
Multi-color polymer pen lithography for oligonucleotide arrays
1Institute of Nanotechnology (INT) & Karlsruhe Nano Micro Facility (KNMF), Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany. michael.hirtz@kit.edu and Physical Institute & Center for Nanotechnology (CeNTech), University of Münster, 48 Münster, Germany.
Abstract:
Multi-color patterning by polymer pen lithography (PPL) was used to fabricate covalently immobilized fluorophore and oligonucleotide arrays with up to five different components. The oligonucleotide arrays offer a virtually unlimited inventory of orthogonal binding tags for self-assembly of proteins as demonstrated by use of the arrays to monitor cell-protein interactions of MCF7 cells.
