[Endocrine loading tests in familial testicular feminization]

The case of 2 children in a family suffering from testicular feminisation of X-linked recessive inheritance, with 46 XY karyotypes, feminine constitution and external genital organs, rudimentary vaginal stump as well as the absence of uterus and tube is described. The histology of the testicles in the labium majus, hormone examinations and the results of choriogonin and testosterone loading are presented. The cases displayed total androgenic insensitiveness.