Related Experiment Video
Updated: Mar 14, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
Published on: February 8, 2022
Different transseptal puncture for different procedures: Optimization of left atrial catheterization guided by
Andrea Radinovic1, Patrizio Mazzone1, Giovanni Landoni2
1Department of Arrhythmology and Cardiac Pacing Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Background:
Left atrial catheterization through transseptal puncture is frequently performed in cardiac catheterization procedures. Appropriate transseptal puncture is critical to achieve procedural success.
Aims:
The aim of the study is to evaluate the feasibility of selective transseptal punctures, using a modified radiofrequency (RF) transseptal needle and transesophageal echocardiography (TEE), in different types of procedures that require specific sites of left atrial catheterization.
Setting And Design:
This was an observational trial in a cardiac catheterization laboratory of a teaching hospital.
Materials And Methods:
Patients undergoing different percutaneous procedures requiring atrial transseptal puncture such as atrial fibrillation (AF) ablation, left atrial appendage (LAA) occlusion, and mitral valve repair were included in the study. All procedures were guided by TEE and an RF transseptal needle targeting a specific region of the septum to perform the puncture.
Statistical Analysis:
The statistical analysis was descriptive only.
Results:
RF-assisted transseptal punctures were performed in six consecutive patients who underwent AF ablation (two patients), LAA closure (two patients), and mitral valve repair (two patients). In all patients, transseptal punctures were performed successfully at the desired site. No adverse events or complications were observed.
Conclusions:
Selective transseptal puncture, using TEE and an RF needle, is a feasible technique that can be used in multiple approaches requiring a precise site of access for left atrial catheterization.
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