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Two different analyzing methods for inhibitory reflexes: Do they yield comparable outcomes?
Michail Koutris1, Kemal S Türker2, Jacobus J van der Weijden1
1Department of Oral Kinesiology, Academic Centre for Dentistry Amsterdam (ACTA), MOVE Research Institute Amsterdam, University of Amsterdam and VU University Amsterdam, Amsterdam, The Netherlands.
Journal of Neuroscience Methods
|October 9, 2016
Summary
Both the cumulative sum (CUSUM) error box and the t-test show good interexaminer reliability for analyzing inhibitory reflexes. These methods are comparable for assessing reflex data.
Area of Science:
- Neuroscience
- Biomedical Engineering
- Physiology
Background:
- Lack of consensus on methodologies for analyzing inhibitory reflexes.
- Commonly used methods include cumulative sum (CUSUM) error box and t-test.
- Need to assess reliability and comparability of these methods.
Purpose of the Study:
- Assess interexaminer reliability of CUSUM error box and t-test for inhibitory reflex analysis.
- Determine if CUSUM and t-test yield similar results.
- Evaluate the comparability of the two analytical methods.
Main Methods:
- Recorded inhibitory jaw reflexes from the masseter muscle.
- Applied electrical stimuli to the upper lip skin.
- Analyzed reflex data using CUSUM error box and t-test by two examiners.
- Assessed outcome variables: reflex parts, area size, and onset.
- Used intraclass correlation coefficient (ICC) for reliability and comparability assessment.
Main Results:
- Fair-to-good to excellent interexaminer reliability for both CUSUM and t-test methods.
- All tested variables showed good reliability.
- Fair-to-good comparability between the CUSUM error box and t-test methods.
Conclusions:
- Both CUSUM error box and t-test are suitable for analyzing inhibitory reflex data.
- The choice between methods can be based on reliability and comparability findings.
- Further research may explore other analytical approaches.

