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Incidentally detected clear cell renal cell carcinoma with rhabdoid differentiation
Venkatesh Krishnamoorthy1, Kiran Krishne Gowda2, Raman Narayana Rao2
1Department of Urology, NU Hospitals, Bengaluru, Karnataka, India.
Abstract:
Renal cell carcinoma with rhabdoid differentiation (RCC-R) has an aggressive biologic behavior and poor prognosis. A recent consensus statement of the International Society of Urological Pathology (ISUP) proposed a nucleolar grading system (ISUP grade) for RCC to replace Fuhrman system and recommended reporting the presence of rhabdoid differentiation and considering tumors with rhabdoid differentiation to be ISUP Grade 4. We report a case of incidentally detected clear cell RCC-R in a 52-year-old man. This is one of the earliest cases of RCC-R (pT1b) detected and first such case from Indian subcontinent.
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