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Vancomycin-resistant enterococci in neonatal stool as a cause of septicemia: Challenges for infection control

Satyendra Kaushal1, Tuhina Banerjee1, Shampa Anupurba1

  • 1Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Indian Journal of Pathology & Microbiology
|October 11, 2016
PubMed

Insights

Vancomycin-resistant enterococci (VRE) sepsis in newborns is rising, with stool carriage identified as a potential source. This highlights gaps in current infection control practices for neonatal care.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Microbiology

Background:

  • Neonatal septicemia poses a significant threat to infant health.
  • Vancomycin-resistant enterococci (VRE) are an emerging cause of healthcare-associated infections.
  • Identifying the source of VRE in neonates is crucial for effective control.

Observation:

  • A case of neonatal septicemia caused by vancomycin-resistant Enterococcus faecalis (VRE) with the vanA genotype is presented.
  • VRE colonization was detected in the stool of the affected neonate.
  • This finding suggests a potential link between neonatal VRE carriage and sepsis development.

Findings:

  • Neonatal septicemia can be caused by VRE, specifically Enterococcus faecalis with the vanA genotype.
  • VRE stool carriage in neonates may serve as an endogenous source for sepsis.
  • The study identified deficiencies in existing infection control protocols.

Implications:

  • Understanding VRE stool carriage is vital for preventing neonatal VRE sepsis.
  • Improved infection control measures are needed to combat the spread of VRE in neonatal intensive care units.
  • Further research is warranted to elucidate the transmission dynamics and develop targeted interventions.

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