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Fluid-Structure Simulations of a Ruptured Intracranial Aneurysm: Constant versus Patient-Specific Wall Thickness
S Voß1, S Glaßer2, T Hoffmann3
1Department of Fluid Dynamics and Technical Flows, University of Magdeburg, Magdeburg, Germany.
Computational and Mathematical Methods in Medicine
|October 11, 2016
Summary
Computational Fluid Dynamics (CFD) simulations for aneurysms are improved by including patient-specific wall thickness. This approach reveals higher stress at rupture sites, crucial for accurate risk assessment.
Area of Science:
- Biomedical Engineering
- Computational Mechanics
- Medical Imaging
Background:
- Computational Fluid Dynamics (CFD) is vital for understanding aneurysm growth and rupture.
- Previous models often assumed rigid vessel walls, limiting rupture risk assessment accuracy.
Purpose of the Study:
- To enhance aneurysm simulation models by incorporating patient-specific wall thickness.
- To compare wall stress distribution using fluid-structure interaction (FSI) with and without constant wall thickness assumptions.
Main Methods:
- Ex vivo preparation of a ruptured intracranial aneurysm.
- Acquisition of local wall thickness using micro-computed tomography (μCT).
- Fluid-structure interaction (FSI) simulations using segmented inner and outer vessel surfaces.
Main Results:
- FSI simulations with patient-specific wall thickness showed significantly higher stress at the rupture site compared to constant wall thickness models.
- Averaged wall stresses were similar, but distribution differed markedly.
- Accurate wall thickness is critical for precise stress localization.
Conclusions:
- Patient-specific wall thickness significantly impacts the accuracy of computational fluid dynamics in predicting aneurysm rupture risk.
- Geometry reconstruction and detailed wall thickness are essential for reliable FSI simulations in vascular biomechanics.
