Related Experiment Video
Updated: Mar 13, 2026

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Dopamine polymerization promoted by a catecholase biomimetic CuII(μ-OH)CuII complex containing a triazine-based
José A F de Oliveira1, Marcos P da Silva1, Bernardo de Souza1
1Laboratório de Bioinorgânica e Cristalografia, Universidade Federal de Santa Catarina, Trindade Campus, Florianópolis, SC 88040-900, Brazil. ademir.neves@ufsc.br adailton.bortoluzzi@ufsc.br.
Abstract:
We describe herein the catecholase-like catalytic activity and dopamine polymerization by using a dinuclear [LCuII(μ-OH)2CuII](ClO4)2 (1) complex where L is the dinucleating triazine-based ligand 6-chloro-N2,N2,N4,N4-tetrakis(pyridin-2-ylmethyl)-1,3,5-triazine-2,4-diamine. The kinetic parameters (kcat = 0.318 s-1, KM = 1.6 × 10-3 mol L-1, and kcat/KM = 198.8 L s-1 mol-1), mechanistic insights into the oxidation of 3,5-di-tert-butyl catechol and early characterization of poly(dopamine) are presented.
Related Concept Videos
Cationic Chain-Growth Polymerization: Mechanism
Ziegler–Natta Chain-Growth Polymerization: Overview
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Drugs Affecting Neurotransmitter Synthesis
Allosteric Proteins-ATCase
Aspartate transcarbamoylase (ATCase) is a cytosolic enzyme that catalyzes the condensation of L-aspartate and carbamoyl phosphate to N-carbamoyl-L-aspartate. This reaction is the first step in pyrimidine biosynthesis. UTP and CTP, the end products of the pyrimidine synthesis...
Radical Chain-Growth Polymerization: Overview

