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Updated: Mar 13, 2026

Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
Pantopaque contrast mimicking intracanalicular vestibular schwannoma
Nicholas L Deep1, Ameet C Patel2, Joseph M Hoxworth2
1Department of Otorhinolaryngology, Mayo Clinic, Phoenix, Arizona, U.S.A.
Abstract:
Pantopaque (iophendylate) is an oily contrast medium historically used during spine imaging. Due to its persistence in the subarachnoid space and the potential to lead to severe arachnoiditis, it is no longer used today. We present a 40-year-old male with new-onset headaches, imbalance, and vertigo. Brain magnetic resonance imaging revealed a 2-mm T1 -hyperintense intracanalicular lesion. Numerous hyperdense foci were scattered throughout the subarachnoid space on computed tomography. Further history revealed the patient received Pantopaque 30 years prior, after sustaining spinal trauma. Remnant Pantopaque contrast is an important differential when evaluating a patient with a suspected intracranial tumor in order to avoid unwarranted surgical intervention. Laryngoscope, 127:1916-1919, 2017.

