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Manufacture and Drug Delivery Applications of Silk Nanoparticles
Published on: October 8, 2016
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Conducting polymers with defined micro- or nanostructures for drug delivery
Dedeepya Uppalapati1, Ben J Boyd2, Sanjay Garg3
1School of Pharmacy, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, Auckland 1023, New Zealand.
Biomaterials
|October 12, 2016
Summary
Conducting polymers with micro/nanostructures offer enhanced drug delivery. These materials provide tunable control over drug release rates and amounts, advancing electrically tunable drug delivery systems.
Area of Science:
- Materials Science
- Polymer Chemistry
- Biomedical Engineering
Background:
- Conducting polymers (CPs) are redox-active materials with adaptable electronic and physical characteristics.
- CPs facilitate ion exchange through redox processes, crucial for electrostatic neutrality and responsive behavior.
Purpose of the Study:
- To review fabrication methods for micro- and nanostructured CPs.
- To discuss recent advancements in applying these structured CPs for drug delivery applications.
Main Methods:
- Fabrication techniques for creating micro- and nanostructured conducting polymers.
- Review of literature on the application of these structured CPs in drug delivery.
Main Results:
- Micro- and nanostructured CPs exhibit significantly larger surface areas compared to conventional CPs.
- These enhanced surface areas facilitate improved ion exchange, leading to faster and larger responses during redox cycling.
- Structured CPs enable increased drug loading capacity and precise control over drug release kinetics.
Conclusions:
- Conducting polymers with defined micro- or nanostructures are promising platforms for advanced drug delivery.
- The tunable nature of CPs, combined with structural control, allows for fine-tuning of drug release profiles.
- These materials represent a maturing technology for electrically tunable drug delivery systems.
Keywords:
Electrically tunable drug deliveryPEDOTPolypyrroleSmart materialsStimuli-responsive drug deliveryTemplateMore Related Videos
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