[Hypoglycemic effect of thymosine in an animal experiment]

Short-term hypoglycemic effect of thymosin was found in intact mice and in animals with alloxan diabetes: single intramuscular administration of 5 mg/kg of thymosin was accompanied by a decrease in glucose content in blood within 15-30 min. Increase in content of immunoreactive insulin in blood was responsible for the hypoglycemia, while the direct insulinotropic effect of thymosin was not observed in isolated pancreas.