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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Craniofacial Secular Change in Recent Mexican Migrants
Katherine Spradley1, Kyra E Stull2, Joseph T Hefner3
11 Department of Anthropology, Texas State University, San Marcos, Texas.
Recent Mexican migrants show subtle craniofacial secular changes compared to historic populations. Historic Hispanics exhibit larger craniofacial dimensions than recent Mexican migrants, indicating distinct morphological trends over time.
Area of Science:
- Anthropology
- Bioarchaeology
- Human Biology
Background:
- Recent economic research indicates Mexican migrants possess higher education and socioeconomic status (SES) than earlier migrants.
- Higher SES and education are linked to secular changes in body form, prompting an analysis of craniofacial complex changes.
- Mexican migrants represent a baseline for studying secular change, unaffected by the American environment.
Purpose of the Study:
- To investigate cranial secular changes in recent Mexican migrants.
- To compare craniofacial morphology between historic and recent Mexican migrants.
- To understand secular trends and biological variation within Mexican migrant populations.
Main Methods:
- Analysis of vault and face size, plus 82 craniofacial interlandmark distances.
- Multivariate adaptive regression splines and basis splines for secular trend assessment in recent migrants.
- Partial Least Squares Discriminant Analysis (PLS-DA) to compare historic and recent samples due to unavailable birth dates for the historic group.
Main Results:
- Significant secular changes over time were detected in both male and female recent Mexican migrants.
- PLS-DA achieved 87% classification accuracy, revealing significant morphological differences between historic and recent groups.
- Historic Hispanic samples displayed larger overall craniofacial dimensions compared to recent Mexican migrants.
Conclusions:
- While secular trends are subtle in recent Mexican migrants, significant craniofacial morphological differences exist between historic and recent Mexican populations in the U.S.
- These findings highlight distinct craniofacial patterns between early and recent Mexican groups, informing future research on migrant adaptation and biological variation.
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