Paget Disease of Bone.

Area of Science:

• Bone Diseases
• Radiology
• Medical Imaging

Background:

• Paget disease (PD) involves abnormal bone turnover due to osteoclast and osteoblast imbalance.
• Evidence suggests a decline in PD incidence, prevalence, and severity.
• The condition is often asymptomatic and incidentally discovered via imaging.

Purpose of the Study:

• To discuss the diverse imaging appearances of Paget disease (PD).
• To highlight the importance of recognizing PD imaging features, particularly on MRI.
• To cover complications associated with Paget disease.

Main Methods:

• Review of imaging characteristics of Paget disease.
• Analysis of radiographic, CT, and MRI findings.
• Discussion of subtle and nonspecific MRI features.

Main Results:

• Radiographs and CT scans show relatively specific PD features.
• MRI findings for PD are subtle and nonspecific.
• PD is increasingly diagnosed via MRI for various pain indications.

Conclusions:

• Familiarity with PD imaging is essential, especially with subtle MRI findings.
• Accurate interpretation of imaging is key for diagnosing PD in an aging population.
• Understanding PD's imaging spectrum aids in managing its complications.