Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diseases of the Liver and Gallbladder01:26

Diseases of the Liver and Gallbladder

2.2K
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Data and the Art of Surgical Preference Card Maintenance.

JAMA surgery·2025
Same author

AI-Driven Tacrolimus Dosing in Transplant Care: Cohort Study.

JMIR AI·2025
Same author

Changing the culture from the bottom Up: Results of a resident-led ergonomics quality improvement initiative.

American journal of surgery·2025
Same author

Single-center perioperative management and 1-year heart transplantation outcomes for patients with adult congenital heart disease.

JHLT open·2025
Same author

Breaking barriers: Successful outcomes of hepatitis C virus D<sup>+</sup>/R<sup>-</sup> transplants in HIV<sup>+</sup> recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2025
Same author

Leveraging Lean Methodology to Improve Compliance With Work-Hour Restrictions.

JAMA surgery·2024

Related Experiment Video

Updated: Mar 13, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

6.3K

Hepatitis B and Hepatocellular Carcinoma.

Alan W Hemming1, Jennifer Berumen1, Kristin Mekeel1

  • 1Division of Transplantation and Hepatobiliary Surgery, Department of Surgery, University of California, San Diego, 9300 Campus Point Drive, # 7745 La Jolla, CA 92037-1300, USA.

Clinics in Liver Disease
|October 16, 2016
PubMed
Summary

Hepatocellular carcinoma (HCC) is a major global cancer threat, often linked to hepatitis B and C. Advances in vaccines and treatments offer hope for reducing future HCC incidence.

Keywords:
Hepatitis BHepatocellular carcinomaLiver ablationLiver resectionLiver transplantation

More Related Videos

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

5.0K
"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

12.3K

Related Experiment Videos

Last Updated: Mar 13, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
12:24

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma

Published on: September 30, 2021

6.3K
Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection
04:11

Author Spotlight: Advancements and Challenges in Hepatitis B Virus Detection

Published on: December 15, 2023

5.0K
"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
10:25

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection

Published on: February 19, 2019

12.3K

Area of Science:

  • Hepatology
  • Oncology
  • Viral Hepatitis

Background:

  • Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality globally.
  • HCC incidence is rising, closely associated with hepatitis B virus (HBV) and hepatitis C virus (HCV) exposure.
  • Chronic viral hepatitis remains a primary driver for HCC development.

Purpose of the Study:

  • To review risk factors and mechanisms of HCC development in hepatitis B patients.
  • To discuss recent advancements in HCC diagnosis and imaging.
  • To outline current management strategies for HCC.

Main Methods:

  • Literature review of risk factors for HCC in hepatitis B.
  • Analysis of underlying molecular mechanisms in hepatocarcinogenesis.
  • Synthesis of current diagnostic and therapeutic approaches for HCC.

Main Results:

  • Identified key risk factors and pathogenic pathways for HBV-related HCC.
  • Highlighted progress in early detection through advanced imaging techniques.
  • Summarized evolving treatment options, including targeted therapies and immunotherapy.

Conclusions:

  • Hepatitis B vaccination and antivirals, alongside direct-acting antivirals for HCV, are crucial for HCC prevention.
  • Early diagnosis and comprehensive management are vital for improving HCC patient outcomes.
  • Continued research into HCC mechanisms and therapies is essential.