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Imaging in Axial Spondyloarthritis: Evaluation of Inflammatory and Structural Changes
1Department of Medicine, University of Alberta, 562 Heritage Medical Research Building, Edmonton, Alberta T6G 2S2, Canada.
Abstract:
The primary use of imaging focuses on diagnostic evaluation, and pelvic radiography is still the primary modality for evaluation of disease in the sacroiliac joints. Its unreliability and inability to directly assess inflammation has led to increasing use of MRI, which directly assesses inflammatory changes as well as the structural changes associated with inflammation. Both radiography and MRI have therefore been incorporated into new classification criteria designed to capture both early and established spondyloarthritis. Fat metaplasia on T1-weighted MRI is an important intermediary tissue on the pathway from inflammation to ankylosis in both the sacroiliac joints and spine.
Insights
Pelvic radiography is a common tool for sacroiliac joint evaluation, but magnetic resonance imaging (MRI) offers superior assessment of inflammation and structural changes in spondyloarthritis. Fat metaplasia on MRI indicates a key stage in disease progression.
Area of Science:
- Radiology
- Rheumatology
- Medical Imaging
Background:
- Pelvic radiography is the primary imaging modality for sacroiliac joint disease.
- Radiography's limitations include unreliability and inability to directly assess inflammation.
- Magnetic resonance imaging (MRI) is increasingly used for its direct assessment of inflammatory and structural changes.
Purpose of the Study:
- To highlight the evolving role of imaging in spondyloarthritis classification.
- To emphasize the diagnostic value of MRI over radiography for sacroiliac joint inflammation.
- To discuss the significance of fat metaplasia in disease progression.
Main Methods:
- Review of current imaging practices in sacroiliac joint evaluation.
- Comparison of diagnostic capabilities of radiography and MRI.
- Analysis of the role of imaging in new spondyloarthritis classification criteria.
Main Results:
- MRI directly assesses inflammatory and structural changes in the sacroiliac joints.
- Fat metaplasia on T1-weighted MRI is an important indicator of disease progression.
- Both radiography and MRI are integrated into new classification criteria for spondyloarthritis.
Conclusions:
- MRI is a crucial tool for evaluating sacroiliac joint inflammation and structural changes in spondyloarthritis.
- Fat metaplasia on MRI signifies an intermediate stage towards ankylosis.
- Combined imaging modalities improve the classification of early and established spondyloarthritis.
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