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Current Perspectives on Imaging for Systemic Lupus Erythematosus, Systemic Sclerosis, and
Sharon L Kolasinski1, Andrew S Chi2, Angel J Lopez-Garib2
1Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, Penn Musculoskeletal Center, 3737 Market Street, Philadelphia, PA 19104, USA.
Rheumatic Diseases Clinics of North America
|October 16, 2016
Summary
Diagnosing systemic rheumatic diseases is challenging due to overlapping symptoms like joint pain. Advanced imaging like MRI and ultrasound improve detection of joint abnormalities beyond plain radiographs.
Area of Science:
- Rheumatology
- Medical Imaging
Background:
- Systemic rheumatic diseases present diagnostic challenges.
- Overlapping symptoms, such as joint pain, can obscure diagnosis.
- Early detection of joint abnormalities is crucial.
Purpose of the Study:
- To evaluate the role of different imaging modalities in diagnosing systemic rheumatic diseases.
- To highlight the diagnostic capabilities of plain radiographs, musculoskeletal ultrasound, and MRI.
Main Methods:
- Review of diagnostic imaging techniques for rheumatic diseases.
- Comparison of plain radiographs with advanced imaging like ultrasound and MRI.
- Discussion of limitations due to disease rarity and lack of longitudinal data.
Main Results:
- Plain radiographs are a suitable initial tool for detecting joint abnormalities.
- Musculoskeletal ultrasound and MRI demonstrate higher sensitivity for synovitis, tenosynovitis, and erosions.
- Current data lacks a comprehensive epidemiological understanding and treatment implications.
Conclusions:
- Advanced imaging offers superior sensitivity in detecting early signs of rheumatic disease activity.
- Further prospective longitudinal studies are needed to clarify the epidemiology and impact on treatment outcomes.
- A multimodal imaging approach may enhance diagnostic accuracy for complex rheumatic conditions.
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