Surgical repair of rabbit tibia osteotomy using isobutyl-2-cyanoacrylate

Isobutyl-2-cyanoacrylate was employed in the surgical repair of the osteotomized rabbit tibia in vivo. Union occurred at 24.3 +/- 3.1 days postoperatively when the adhesive had been used, compared with 35.5 +/- 3.6 days when no intervention was implemented. Healing of the osteotomy was not aided by external fixation or immobilization in either case. The results indicate the feasibility of using isobutyl-2-cyanoacrylate in the repair of load-bearing bones.