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Surgical Correction for Pediatric Epiblepharon and Trichiasis

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Tissue Engineering in Ophthalmology: Implications for Eyelid Reconstruction.

Michelle T Sun¹, Andrea J O'Connor, John Wood

¹*Discipline of Ophthalmology and Visual Sciences, South Australian Institute of Ophthalmology and Royal Adelaide Hospital, Adelaide, South Australia, Australia; and †Department of Chemical and Biomolecular Engineering, Particulate Fluids Processing Centre, The University of Melbourne, Melbourne, Victoria, Australia.

Ophthalmic Plastic and Reconstructive Surgery

|October 18, 2016

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Tissue engineering offers promising solutions for ophthalmic plastic surgery, particularly for eyelid reconstruction. This review explores current applications and future potential in regenerative ophthalmology.

Area of Science:

Biomedical Engineering
Regenerative Medicine
Ophthalmology

Background:

Tissue engineering aims to create functional tissue replacements for defect repair.
Significant research has focused on bioengineering applications in ophthalmology over recent decades.

Purpose of the Study:

To review the literature on tissue engineering applications in ophthalmology.
To specifically focus on ophthalmic plastic surgery and eyelid reconstruction.

Main Methods:

A comprehensive literature search was conducted on the MEDLINE database.
Keywords used included "bioengineering," "tissue engineering," and "ophthalmology."
English-language articles were included in the review.

Main Results:

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Corneal Tissue Engineering: An In Vitro Model of the Stromal-nerve Interactions of the Human Cornea

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Extensive research exists on corneal tissue engineering.
Other ocular structures investigated include the conjunctiva, lacrimal gland, and orbital bone.
Potential applications for eyelid reconstruction using tissue engineering were identified.

Conclusions:

Tissue engineering is pivotal for the future of regenerative and reconstructive medicine.
Ophthalmic plastic surgery stands to benefit significantly from tissue engineering advancements.