Studies on hemolytic activity of bisphenol A diglycidyl methacrylate (BIS-GMA)

To clarify the high hemolytic activity of BIS-GMA, the molar concentration producing 50% hemolysis (H50) and the partition coefficient inoctanol-water were determined using BIS-GMA and various types of methacrylates. It is suggested that the strong hemolytic potency of BIS-GMA is due to the high hydrophobic nature of the compound.