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Abstract:
A patient with myasthenia gravis who developed skeletal metastases 9 years following the complete excision of a thymoma is described. Several aspects of the case were noteworthy: (1) the original thymoma failed to demonstrate evidence of capsular invasion, (2) the association of myasthenia gravis with metastatic predominantly epithelial cell thymoma has not been previously documented, and (3) the time to development of metastatic disease is the second longest interval reported in the medical literature. The clinical implications of these features are discussed.