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Published on: May 21, 2017
Acquired discrete subaortic stenosis late after mitral valve replacement
Jagdish C Mohan1, Madhu Shukla1, Vishwas Mohan1
1Fortis Institute of Cardiac Sciences, Fortis Hospital, Shalimar Bagh, New Delhi 88, India.
Acquired left ventricular outflow obstruction is rare after mitral valve replacement (MVR). This study highlights two cases of severe subaortic stenosis developing five years post-MVR, emphasizing the need for vigilance in symptomatic patients.
Area of Science:
- Cardiology
- Cardiac Surgery
- Biomedical Engineering
Background:
- Acquired left ventricular outflow obstruction (LVOTO) is uncommon after mitral valve replacement (MVR).
- Previous reports on LVOTO post-MVR are limited.
- Bioprosthetic valves are frequently used in MVR procedures.
Observation:
- Two female patients developed severe discrete subaortic stenosis (DSS) five years after MVR.
- Both patients received a 27-mm porcine Carpentier-Edwards bioprosthesis.
- Mitral valve leaflets were preserved in both cases during MVR.
Findings:
- Preservation of the subvalvular apparatus during bioprosthetic MVR may pose a risk for late-onset LVOTO.
- Discrete subaortic stenosis can manifest years after mitral valve surgery.
- The specific type of bioprosthesis (porcine Carpentier-Edwards) and valve size (27-mm) were noted.
Implications:
- Clinicians should consider the potential for very late LVOTO in patients with bioprosthetic MVR, especially with subvalvular apparatus preservation.
- Symptomatic patients with a history of MVR require thorough evaluation for outflow tract obstruction.
- Further research is warranted to elucidate the mechanisms and incidence of late LVOTO after MVR with leaflet preservation.
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