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Updated: Mar 13, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
4-mm-diameter three-dimensional imaging endoscope with steerable camera for minimally invasive surgery (3-D-MARVEL)
Sam Y Bae1, Ronald J Korniski1, Michael Shearn1
1Jet Propulsion Laboratory , California Institute of Technology, 4800 Oak Grove Drive, Pasadena, California 91109, United States.
A novel 4-mm stereo imaging endoscope, the Multiangle, Rear-Viewing Endoscopic Tool (MARVEL), achieves high-resolution 3-D visualization for minimally invasive surgery. This compact endoscope offers side-to-side panning, enhancing surgical capabilities in confined spaces.
Area of Science:
- Medical Endoscopy
- Surgical Imaging Technology
- Minimally Invasive Surgery
Background:
- High-resolution 3-D (stereo) imaging is crucial for minimally invasive surgery, particularly in confined surgical fields like neurosurgery.
- Current stereo imaging endoscopes typically exceed 4-mm in diameter, limiting their application in space-constrained procedures.
Purpose of the Study:
- To develop a compact, 4-mm diameter stereo imaging endoscope for enhanced visualization in minimally invasive surgery.
- To introduce a novel endoscope system capable of side-to-side panning for improved surgical maneuverability.
Main Methods:
- Development of a single-lens stereo imaging endoscope, termed Multiangle, Rear-Viewing Endoscopic Tool (MARVEL).
- Integration of complementary multibandpass filter (CMBF) technology for achieving 3-D imaging.
- Incorporation of a side-to-side panning actuation mechanism within the endoscope.
Main Results:
- Successful development of a 4-mm diameter endoscope capable of high-resolution 3-D imaging.
- Demonstration of a unique side-to-side panning capability over a specific angular range.
- Integration of a single-lens CMBF camera with illumination and actuation mechanisms.
Conclusions:
- The MARVEL endoscope offers a significant advancement in compact 3-D surgical visualization.
- This technology has the potential to improve surgical precision and outcomes in space-constrained procedures.
- The developed endoscope provides a unique combination of 3-D imaging and maneuverability for surgical applications.
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