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Updated: Sep 20, 2026

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
Published on: October 20, 2021
Soft bioelectronics for wireless drug delivery: programmable, minimally invasive and closed-loop therapeutics
Feng Zhang1, Fuchang Sun1, Zheng Yan1,2
1Department of Chemical and Biomedical Engineering, University of Missouri, Columbia, MO USA.
Abstract:
Soft bioelectronics is reshaping drug delivery from passive dosing to programmable, tissue-interfaced therapeutics. This Review examines the co-design of soft materials, wireless power, drug reservoirs, release mechanisms and feedback control for wearable and minimally invasive implantable therapeutic systems. We organize the field around key constraints including controllability, reversibility, payload capacity, dosing precision, drug stability and feedback latency, guiding the development of adaptive closed-loop drug delivery platforms for clinical translation.
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