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Synthesis and biological activity of dibenz[c,e]azepines
H Y Aboul-Enein1, S E Ibrahim, M Khalifa
1Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Abstract:
Synthesis and pharmacological screening of 68 dibenz[c,e]azepines are described. All were inactive as antidepressant agents, but two compounds showed good anticonvulsant activity. The structure-activity relationships of this class of compounds are discussed.