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Related Experiment Video

Updated: Mar 13, 2026

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Microneedling: A Comprehensive Review.

Angela Hou1, Brandon Cohen, Adele Haimovic

  • 1*All authors are affiliated with the Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|October 19, 2016
PubMed
Summary
This summary is machine-generated.

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Microneedling therapy, using fine needles to create micro-injuries, effectively treats various skin conditions like acne and scars by stimulating collagen. While generally safe, common side effects include temporary redness and pigmentation changes.

Area of Science:

  • Dermatology
  • Aesthetic Medicine
  • Regenerative Medicine

Background:

  • Microneedling is a minimally invasive procedure creating epidermal micro-injuries.
  • These micro-injuries stimulate growth factors and collagen production.
  • The epidermis remains largely intact, minimizing adverse events.

Purpose of the Study:

  • To comprehensively review microneedling procedures in human subjects.
  • To explore the diverse applications of microneedling in dermatology.

Main Methods:

  • Conducted a literature search using PubMed/MEDLINE and Science Direct.
  • Included studies on microneedling in human subjects, prioritizing randomized trials.
  • Utilized search terms: "microneedling," "needling," and "percutaneous collagen induction."

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Main Results:

  • Microneedling demonstrates efficacy and safety for treating scars, acne, melasma, photodamage, and alopecia.
  • It also facilitates transdermal drug delivery.
  • Common transient adverse events include erythema and postinflammatory hyperpigmentation; permanent events are rare.

Conclusions:

  • Microneedling is an effective and safe therapeutic option for numerous dermatologic conditions.
  • Further large-scale, randomized controlled trials are needed.
  • More data is required for diverse skin types and conditions.