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Zfra induction of memory anticancer response via a novel immune cell
Wan-Pei Su1, Wan-Jan Wang1, Chun-I Sze2
1Institute of Molecular Medicine, National Cheng Kung University , Tainan, Taiwan, ROC.
Oncoimmunology
|October 21, 2016
Abstract:
When naive mice receive short Zfra peptides via tail vein injections, they develop lifetime resistance to growth of many cancer xenografts, due to activation of a novel spleen memory Hyal-2+ CD3- CD19- Z lymphocyte. In vitro education of spleen cells with Zfra activates Z cell for conferring memory anticancer response in vivo.
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