Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Pre-ejection period controlled cardiac pacemaker].

M Schaldach

    Biomedizinische Technik. Biomedical Engineering
    |July 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a novel rate-adaptive pacemaker controlled by the pre-ejection period (PEP). This innovative approach enhances pacing rate adaptation to meet metabolic demands, improving patient outcomes.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Quantitative ATR spectroscopy: some basic considerations.

    Applied optics·2010
    Same author

    [Not Available].

    Herzschrittmachertherapie & Elektrophysiologie·2009
    Same author

    A polyhydroxybutyrate biodegradable stent: preliminary experience in the rabbit.

    Cardiovascular and interventional radiology·2002
    Same author

    [An implantable telemetry system for impedance spectroscopy].

    Biomedizinische Technik. Biomedical engineering·2002
    Same author

    A new detection algorithm for implantable cardioverter defibrillator.

    Biomedizinische Technik. Biomedical engineering·2001
    Same author

    The effects of orthostasis on the ventricular-evoked response.

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2001

    Area of Science:

    • Biomedical Engineering
    • Cardiology
    • Physiology

    Context:

    • Physiologic adaptation of pacing rate is crucial for patients with chronotropic incompetence.
    • Existing control parameters have limitations in specificity and response time.
    • Central hemodynamic parameters offer potential for improved rate control.

    Purpose:

    • To present a novel rate-adaptive pacemaker concept controlled by the pre-ejection period (PEP).
    • To investigate the linear proportionality between PEP and cardiac cycle length for rate adaptation.
    • To evaluate the clinical efficacy of PEP as a control parameter for pacemakers.

    Summary:

    • A PEP-controlled rate-adaptive pacemaker system is proposed, utilizing the inverse relationship between PEP and cardiac cycle length.

    Related Experiment Videos

  • The system adapts pacing rate based on changes in sympathetic tone, responding to physical and emotional stress.
  • Clinical results demonstrate high sensitivity and specificity of PEP in matching pacing rate to metabolic demand.

    • Impact:

    • Offers a more specific and sensitive method for rate-adaptive pacing, particularly beneficial for patients with low cardiac reserve.
    • Enhances the quality of life for pacemaker patients by optimizing cardiac output during varying physiological conditions.
    • Paves the way for advanced, multiprogrammable implantable devices with improved patient-specific rate control.