PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers

Area of Science:

• Public Health
• Infectious Disease Prevention
• HIV/AIDS Epidemiology

Background:

• HIV epidemics in the Asia-Pacific disproportionately affect men who have sex with men (MSM) and other key populations.
• Pre-exposure prophylaxis (PrEP) offers an effective HIV prevention strategy with the potential to significantly alter the epidemic's trajectory in the region.

Purpose of the Study:

• To review the progress of PrEP implementation in the Asia-Pacific region.
• To identify opportunities and barriers associated with PrEP uptake and access.

Main Methods:

• Review of current PrEP implementation status, including awareness, utilization, and existing programs.
• Analysis of barriers such as knowledge gaps, access limitations, cost, stigma, and legal restrictions.
• Examination of emerging implementation models and WHO guidelines.

Main Results:

• PrEP awareness and utilization remain low among MSM in the Asia-Pacific, despite high willingness to use it among those aware.
• Significant barriers include poor knowledge, limited access, inadequate prevention programs, high costs, stigma, and restrictive laws.
• Novel approaches like researcher-, facility-, and community-led models are emerging, alongside WHO recommendations and national guidelines.

Conclusions:

• Integrating PrEP into HIV prevention packages is crucial for the Asia-Pacific region, necessitating adequate resourcing.
• The coming years should focus on transitioning from pilot projects to widespread PrEP access and expanded HIV prevention efforts.