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Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

5.6K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
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Related Experiment Video

Updated: Mar 13, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
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Small nonfunctional parathyroid cysts: single institution experience.

Ljubica Fustar Preradovic1, Davorin Danic, Radan Dzodic

  • 1Department of Pathology and Cytology, Dr. Josip Bencevic General Hospital, Slavonski Brod, Croatia.

Endocrine Journal
|October 21, 2016
PubMed
Summary
This summary is machine-generated.

Parathyroid cysts are rare neck lesions that can mimic other conditions. Diagnosis and treatment depend on cyst function and size, with ultrasound-guided fine-needle aspiration crucial for parathyroid cyst identification.

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Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Diagnostic Imaging

Background:

  • Parathyroid cysts (PCs) are rare, comprising less than 1% of parathyroid lesions.
  • They often present diagnostic challenges, mimicking other cystic neck masses.
  • PCs can be functional (hormone-secreting) or nonfunctional.

Observation:

  • This study presents four cases of nonfunctional parathyroid cysts in female patients.
  • Diagnostic methods included physical examination, ultrasonography, and ultrasound-guided fine-needle aspiration biopsy (UG-FNA).
  • Cytologic analysis and parathyroid hormone (PTH) level determination in aspirate and serum were performed.

Findings:

  • Two patients with nonfunctional PCs experienced remission after aspiration.
  • One patient required surgery for compression syndrome and vocal cord paresis.
  • Another patient underwent surgical removal due to cyst recurrence.

Implications:

  • Accurate diagnosis of cystic neck masses is critical for appropriate management.
  • Ultrasonography with UG-FNA and PTH level measurement are essential for diagnosing PCs.
  • Treatment strategies vary from aspiration for small nonfunctional cysts to surgery for large or functional cysts.