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Life-Threatening Thrombo-embolic Events in a Case of Dengue Hemorrhagic Fever

Arun Agarwal1, Samiksha Sharma2, Mala Airun3

  • 1Senior Consultant and Head, Department of Internal Medicine.

The Journal of the Association of Physicians of India
|October 21, 2016
PubMed

In Dengue Hemorrhagic Fever (DHF), hemorrhagic manifestations are common but thrombotic events are uncommonly reported, despite the wide range of increased procoagulant activity during Dengue Fever illness. We report a case of a 55-year-old man of Asian Indian ethnicity who developed large vein thrombotic event -Deep Vein Thrombosis (DVT) and Pulmonary Embolism (PE) in the acute phase of DHF. His condition was further complicated by associated thrombocytopenia. The etiological connections between dengue viral infection with thrombocytopenia, DVT/PE and abnormal thrombophilia profile as well as the treatment dilemmas posed in treating a patient of DF with hemorrhagic manifestations and associated DVT/PE, and the role of eltrombopag are discussed.

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