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[Ocular syphilis: 9 cases].

A S Gauthier1, S Tea1, L Hustache Mathieu2

  • 1Service d'ophtalmologie, CHU Jean-Minjoz, 2, boulevard Fleming, 25030 Besançon, France.

Journal Francais D'Ophtalmologie
|October 22, 2016
PubMed
Summary
This summary is machine-generated.

Ocular syphilis, a rising concern, can affect all eye structures. Early diagnosis and penicillin G treatment significantly improve vision in affected patients.

Keywords:
KeratitisKératiteOcular syphilisPapillary edemaSyphilis oculaireUveitisUvéiteŒdème papillaire

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Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Public Health

Background:

  • Syphilis can manifest with diverse ocular involvements, affecting all structures of the eye.
  • Ocular syphilis is a re-emerging infectious disease that requires prompt recognition and management.

Observation:

  • A retrospective study identified 9 male patients with ocular syphilis over a 10-year period (March 2004-April 2014).
  • Common presentations included interstitial keratitis, uveitis, chorioretinitis, and bilateral papillary edema.
  • Decreased visual acuity was the primary presenting symptom in all patients.

Findings:

  • Intravenous penicillin G administered for 3 weeks resulted in significant visual acuity improvement in all patients.
  • Initial visual acuity ranged from 'counting fingers' to 0.6, improving to 0.5-1.0 post-treatment.
  • The mean age of patients at diagnosis was 52.6 years.

Implications:

  • Ocular syphilis should be systematically investigated in patients presenting with inflammatory eye conditions or papilledema.
  • Increased awareness and diagnostic vigilance are crucial given the rising incidence of syphilis.
  • Prompt treatment can lead to favorable visual outcomes, underscoring the importance of early detection.