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Published on: March 8, 2012
Characteristics of HPV infection in women at risk in Western Algeria
N Masdoua1, L Boublenza1, H Hassaine1
1Laboratoire de microbiologie appliquée à l'agro-alimentaire, au biomédical et à l'environnement (LAMAABE), université de Tlemcen, Ex. complexe biomédical, Imama, Bloc C, BP 119, 13000 Tlemcen, Algeria.
Objectives:
We aimed to characterize HPV infections and cervical lesions in Western Algeria.
Patients And Methods:
A total of 96 cervical samples obtained from women at risk of HPV infection (HIV-1-infected or presenting with a gynecological disease) were analyzed to characterize this infection and search for cytological abnormalities.
Results:
A total of 60% of women at risk had an HPV infection. The rate of high-risk HPV (HR-HPV) infection among these women was 84.5% and that of intraepithelial lesions was 29.3%. The frequency of HPV infection was significantly higher among HIV-1-infected patients. An association between the presence of HR-HPV and the polygamy of the partner was observed. An association between cytological abnormalities and the use of oral contraceptives was observed among HIV-1-infected women.
Conclusion:
Given the high frequency of HPV infection in this at risk population, close monitoring and regular gynecological screening are essential.
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